The ACAB project
What is it?
ACAB is a three-year scientific project aimed at improving the environment and health in Tuscany. The acronym ACAB refers to the content of the study: ACAB – Attributable CAncer Burden in Tuscany: smoking, environmental and occupational risk factors and evaluation of prevention strategies. That is: attributable cancer burden due to smoking, air pollution, environmental, and occupational carcinogens in Tuscany and evaluation of prevention policies.
Who is funding it?
The project is funded by Tuscany Region in the framework of the Health Research Call “Bando Ricerca Salute” 2018.
Who is participating in the project?
ACAB is coordinated by the Institute for cancer research, prevention and oncological network (ISPRO). The Local Health Authority (Azienda USL Toscana Centro) and the Department of Statistics, Computer Science, Applications of the University of Florence are participating in the project. The Regional Health Agency (ARS) of Tuscany, the Institute for Maternal and Child health IRCCS ‘Burlo Garofolo’ of Trieste and the LaMMA Consortium collaborate as external partners.
What does ACAB aim at?
First of all, ACAB will provide a description of the state of health of the Tuscan population, drawing up for each Local Health Authority and for each territorial district an updated estimate of the number of deaths, years of life lost or years lived with disability due to the main pathologies.
It will then focus on the number of deaths and years of life lived with disability caused by cancer due to three risk factors: tobacco smoke, air pollution, and exposure to carcinogenic substances in the workplace.
ACAB will quantify the burden of disease that could have been avoided by reducing or eliminating the three risk factors and will assess the benefit (today and in the future) of implementing tobacco control policies, curbing emissions of particulate matter and other air pollutants, and making workplaces healthier.
In a nutshell, ACAB serves to calculate how much health we have lost due to important risk factors and how much we could gain by implementing effective prevention interventions. This information is essential to guide public health choices and make us more aware that protecting the environment and changing our lifestyles is fundamental to improving the health of the community in which we live.
ACAB’s symbol is a flower: the Crocus Etruscus, chosen by 500 experts from the Italian Botanical Society as the representative plant of the Tuscany region. Delicate, colourful, brave.
Istituto per lo Studio, la Rete e la Prevenzione Oncologica (ISPRO)
Dipartimento di Statistica, Informatica, Applicazioni (DISIA), Università di Firenze
Dipartimento di Prevenzione, Azienda USL Toscana Centro (AUSL TC)
Osservatorio di Epidemiologia
IRCCS materno infantile Burlo Garofolo
Divisione Fisica dell’Atmosfera
Timeline of project developements
Collection of epidemiological data and of data on exposure to smoking, air pollution and to the main occupational carcinogens
Development of methods for DALYs estimation
Estimation of DALYs for the leading diseases and for cancers
Definition / estimation of dose-response curves
Development of a compartmental model for the dynamics of smoking
Estimation of the burden of disease from cancer due to smoking, to air pollution and to the main occupational carcinogens
Formulation of counterfactual scenarios for smoking habits and for exposure to air pollution and occupational carcinogens and health impact assessment through the compartmental.